PTX	Paclitaxel
NCI	National Cancer Institute
T. brevifolia	Taxus brevifolia
BMS	Bristol-Myers Squibb
FDA	Food and Drug Administration
EMA	European Medicines Agency
NSCLC	Non-small-cell lung carcinoma
PDAC	Pancreatic ductal adenocarcinoma
MVA	Mevalonate
MEP	methylerythritol phosphate
IPP	Isopentenyl pyrophosphate
DMAPP	Dimethylalyl pyrophosphate
taxadiene	Taxa-4(5),11(12)-diene
IDI	Isopentenyldiphosphate isomerase
GPPS	Geranylpyrophosphate synthase
GGPPS	Geranylgeranylpyrophosphate synthase
10-DAB	10-deacetyl baccatin III
E. coli	Escherichia coli
S. cerevisiae	Sacharomyces cerevisiae
B. subtillis	Bacillus subtilis
CrEL	Cremophor EL
MTD	Maximum authorized dose
ROS	Reactive-oxygen species
GSH	Glutathione
PEG	polyethylenglycoly
AUC	Area under the concentration–time curve
P-gp	P-glycoprotein
mPEG-PDLLA	Monomethoxy-poly (ethylene glycol)-block-poly(d,l-lactide)
PVP-b-PNIPAAM	poly-(vinylpyrrolidone)-b–poly-(N-isopropyl acryl-amide)
WHO	Word Health Organization
MTA	Microtubule Targeting Agent
ER	Endoplasmic reticulum
Bcl-2	B-cell Leukemia 2
BAX	Bcl-2-associated X protein
MMP	Mitochondrial membrane potential
ATG5	Autophagy protein 5
TLR4	Toll-like receptor 4
PAMPs	Pathogen-associated molecular patterns
HIF-1	Hypoxia-inducible factor 1
KRT17	keratin 17
FNDC5	Fibronectin type III domain-containing protein 5
MDR1	Multidrug resistance-associated protein 1
ABC	ATP-binding cassette
RTK	Receptor tyrosine kinase
TKIs	Inhibitors of receptor tyrosine kinases
MUC-1	Mucin 1
PFL	Penfluridol
FoxM1	Forkhead protein 1
PHB1	Prohibitin 1
SSTA	Somatostatin analogue
SSTR	Somatostatin receptor
MAPK	Mitogen-Activated Protein Kinase
LdA	Lactate dehydrogenase
Pdk2	Pyruvate dehydrogenase kinase 2
PN	Peripheral neuropathy (PN)
lncRNA	Long noncoding RNA
EGOT	Eosinophil granule ontogeny transcript
FER1L4	Fer-1-like family member 4
LINC-PINT	lncRNA intergenic non-protein-coding RNA p53-induced transcript
UCA1	Urothelial Carcinoma-Associated 1
ABCB1	ATP Binding Cassette Subfamily B Member
LINC01118	Long Intergenic Non-Coding RNA 1118
lncRNA SDHAP1	LnRNA succinate dehydrogenase complex flavoprotein subunit A pseudogene 1
EIF4G2	Eukaryotic translation initiation factor 4 gamma 2
CCAT1	Colon cancer-associated transcript 1
FSCN1	Fascin1
CAAs	Cancer-associated adipocytes
CAFs	Cancer-associated fibroblasts
(CTSL	Cathepsin L
SIK2	Salt-inducible kinase 2
IKBKB	IκB kinase β
E2F5	E2F transcription factor 5
MCT1	Monocarboxylic acid solute transporter 1
KEAP1	Kelch-like ECH-associated protein 1
ITGB1	Upregulation of integrin beta-1
ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1