Table 6.

In vitro activity of oleuropein, verbascoside and derivatives (hydroxytyrosol and caffeic acid, respectively) against bacterial strains representative for Gram-positive and Gram-negative pathogens. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of each compound were determined by the broth microdilution method and expressed as µg/mL.

Bacterial Strain	Oleuropein		Verbascoside		Hydroxytyrosol		Caffeic Acid
	MIC	MBC	MIC	MBC	MIC	MBC	MIC	MBC
P. aeruginosa AC12a	>1024	>1024	>1024	>1024	>256	>256	>256	>256
S. aureus Sa1	1024	1024	>1024	>1024	256	256	256	>256
E. faecalis ATCC29212	>1024	>1024	>1024	>1024	>256	>256	>256	>256
E. coli K2P	>1024	>1024	>1024	>1024	>256	>256	>256	>256