Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibition of human cytomegalovirus (HCMV) and HIV-1 by sequestration of Sp1. (a) IFI16 sequesters the host transcription factor Sp1 to inhibit gene expression of the HCMV UL44 and UL54 gene promoters. (b) Nuclear PYHIN proteins reduce the availability of Sp1 to suppress LTR-driven viral gene expression.
