Table 2.
Serum and liver biochemical analysis of mice at the end of the study.
| Variable | C | E | E + LP | E + HP |
|---|---|---|---|---|
| Serum | ||||
| AST (IU/L) | 56.3 ± 7.1 b | 67.6 ± 11.6 a | 58.0 ± 11.2 b | 58.0 ± 6.3 b |
| ALT (IU/L) | 25.8 ± 3.6 b | 30.9 ± 6.5 a | 24.6 ± 6.8 b | 24.5 ± 4.5 b |
| γ-GT (IU/L) | 1.5 ± 0.7 b | 2.6 ± 0.1 a | 1.6 ± 0.6 b | 1.7 ± 0.5 b |
| TGs (mg/dL) | 76.0 ± 16.9 b | 97.9 ± 18.9 a | 102.8 ± 21.6 a | 90.4 ± 16.5 ab |
| Endotoxin (EU/mL) | 0.18 ± 0.05 b | 0.28 ± 0.09 a | 0.15 ± 0.09 b | 0.06 ± 0.03 c |
| Liver | ||||
| Liver index (%) | 3.8 ± 0.2 c | 4.4 ± 0.2 a | 4.0 ± 0.2 bc | 4.0 ± 0.4 b |
| TGs (μmol/liver) | 36.0 ± 9.1 c | 62.5 ± 18.7 a | 50.6 ± 9.1 b | 49.6 ± 6.9 b |
| TNF-α (pg/mg protein) | 130.4 ± 35.9 b | 155.1 ± 20.8 a | 111.4 ± 11.0 b | 125.8 ± 9.8 b |
| IL-1β (pg/mg protein) | 129.4± 21.9 b | 161.5 ± 12.4 a | 113.9 ± 35.0 b | 119.2 ± 12.0 b |
Values are expressed as mean ± SD (n = 10). abc Significant difference (p < 0.05) is identified by different letters in the same row. C, control group; E, ethanol group; E + LP, low-dose pitaya peel extract (PPE) group; E + HP, high-dose PPE group. AST, aspartate transaminase; ALT, alanine transaminase; γ-GT, gamma glutamyl transpeptidase; TGs, triglycerides. Liver index (%) = liver weight/body weight.