Table 3.
Sex-specific association of LV size parameters per 1-SD increase (crude and adjusted for age) with presence of severe AR, defined as regurgitation fraction (RegF) ≥ 30% on cardiovascular magnetic resonance imaging (CMR).
| LV Size Parameter | OR (95%CI) Per 1SD | p-Value | OR (95%CI) Per 1SD | p-Value |
|---|---|---|---|---|
| Crude | Adjusted for Age | |||
| MEN | ||||
| Echo LVEDD | 3.80 [2.29–6.30] | <0.001 | 4.47 [2.61–7.66] | <0.001 |
| Echo LVEDV | 3.50 [2.12–5.53] | <0.001 | 4.26 [2.57–7.05] | <0.001 |
| Echo LVEDV/BSA | 3.93 [2.42–6.39] | <0.001 | 4.83 [2.81–8.31] | <0.001 |
| CMR LVEDV | 3.55 [2.20–5.73] | <0.001 | 3.74 [2.30–6.08] | <0.001 |
| CMR LVEDV/BSA | 4.04 [2.42–6.73] | <0.001 | 4.17 [2.49–6.97] | <0.001 |
| Women | ||||
| Echo LVEDD | 2.30 [1.33–3.98] | 0.003 | 2.48 [1.40–4.38] | 0.002 |
| Echo LVEDV | 2.12 [1.25–3.61] | 0.005 | 2.26 [1.31–3.93] | 0.004 |
| Echo LVEDV/BSA | 2.09 [1.23–3.53] | 0.006 | 2.25 [1.30–3.89] | 0.004 |
| CMR LVEDV | 2.63 [1.53–4.51] | <0.001 | 2.91 [1.65–5.14] | <0.001 |
| CMR LVEDV/BSA | 2.53 [1.49–4.28] | 0.001 | 2.74 [1.57–4.80] | <0.001 |
LVEDD indicates left ventricular end-diastolic diameter; LVEDV, left ventricular end-diastolic volume; BSA, body surface area; CMR, cardiovascular magnetic resonance imaging.