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. 2020 Dec 16;25(24):5960. doi: 10.3390/molecules25245960

Figure 6.

Figure 6

Effect of 11Cha1 on ATP-induced K+ outflow from cells. THP-1 cells were seeded and differentiated by 50 nM PMA for 48 h and then primed with 1 μg/mL LPS for 4 h. The cells were pre-treated with or without 11Cha1 (30 µM) for 30 min and then treated with 5 mM ATP for another 30 min. After treatment, intracellular potassium content was determined using Potassium Assay Kit (MyBioSource, San Diego, CA, USA) according to manufacturer’s protocols. Data are expressed as mean ± SEM of five independent determinations. One-way ANOVA by Newman Keuls post hoc test is used. The analyses of P (AVOVA) indicates P < 0.001.