Figure 1.

The cytotoxic activity of silver nitrate (AgNO₃), metronidazole, 4-hydroxymethylpyridine, ((MTZ)₂Ag)NO₃, and ((4-OHMePy)₂Ag)NO₃ against PANC-1 and 1.2B4 cells. The cells were treated with the tested compounds in the 0–300 µM concentration range, and cisplatin (0–100 µM) was employed as a positive control. After 72-h of incubation, cytotoxicity was determined using the MTT assay. Data are expressed as means ± SD from three to five independent experiments. * p < 0.05; ** p < 0.01, *** p < 0.001 in comparison to untreated cells (negative control).