Table 1.
Demographic subject data.
| Parameters | Control | POAG | p-Value a |
|---|---|---|---|
| N | 20 | 66 | |
| Age (years) | |||
| Mean ± SD | 69.4 ± 9.0 | 65.4 ± 11.7 | 0.3388 |
| range | 55.0–88.0 | 24.0–84.0 | |
| Sex | |||
| Men, n (%) | 7 (35.0) | 37 (56.0) | 0.1278 |
| Women, n (%) | 13 (65.0) | 29 (44.0) | |
| sBP (mmHg) | |||
| Mean ± SD | 135.9 ± 17.9 | 139.3 ± 21.9 | |
| range | 105.0–172.0 | 102.0–191.0 | |
| dBP (mmHg) | |||
| Mean ± SD | 78.3 ± 11.1 | 80.8 ± 12.8 | 0.4738 |
| range | 62.0–95.0 | 52.0–110.0 | |
| BCVA (LogMAR) | |||
| Mean ± SD | 0.28 ± 0.44 | 0.03 ± 0.34 | <0.0001 ** |
| range | −0.08–1.00 | −0.08–1.70 | |
| IOP (mmHg) | |||
| Mean ± SD | 14.7 ± 2.8 | 15.9 ± 6.7 | 0.8492 |
| range | 11.0–22.0 | 6.0–52.0 | |
| Glaucoma medication (n) | |||
| Mean ± SD | 1.5 ± 1.2 | ||
| range | 0.0–5.0 | ||
| Types of glaucoma medication | |||
| Prostaglandins, n (%) | 51 (77.2) | ||
| β-blockers, n (%) | 30 (45.5) | ||
| CAI, n (%) | 15 (22.7) | ||
| Cholinergics, n (%) | 1 (1.5) |
a Comparison between the controls and the POAG groups by using the Mann–Whitney U test for continuous data and by using Fisher’s exact probability test for categorical data. The ** corresponds to the significance level at 1% (p < 0.01). N, number of participants; SD, standard deviation; POAG, primary open-angle glaucoma; sBP, systolic blood pressure; dBP, diastolic blood pressure; BCVA, best-corrected visual acuity; logMAR, logarithm of the minimum angle of resolution; IOP, intraocular pressure; CAI, carbonic anhydrase inhibitors.