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. 2020 Dec 21;21(24):9770. doi: 10.3390/ijms21249770

Figure 2.

Figure 2

Factors contributing to the development of leaky gut and its relationship to autoimmune diseases. Diet, genetic susceptibility, and environmental conditions, among others, affect the intestinal epithelial barrier integrity. This imbalance leads to compromised barrier integrity and contributes to several diseases.