Table 6.
Sensitivity analysis for occupational history and T2DM and dementia (for the subgroup of 120,299 participants).
| Cumulative Occupational Exposure Over Years—Standardised Values (Standardised (P × L) * Years) *** | T2DM OR (95% CI) Univariable |
T2DM OR (95% CI) Multivariable * |
Dementia OR (95% CI) Univariable |
Dementia OR (95% CI) Multivariable ** |
|---|---|---|---|---|
| Dust | 1.09 (1.06–1.11) | 1.00 (0.97–1.03) | 1.00 (0.54–1.23) | 0.95 (0.49–1.21) |
| Fumes | 1.07 (1.04–1.09) | 0.98 (0.95–1.01) | 0.99 (0.46–1.19) | 0.95 (0.42–1.18) |
| Diesel engine exhaust | 1.07 (1.05–1.09) | 0.98 (0.94–1.01) | 1.10 (0.86–1.20) | 1.08 (0.83–1.18) |
| Mineral dust | 1.08 (1.05–1.10) | 1.01 (0.97–1.03) | 1.07 (0.73–1.23) | 1.05 (0.69–1.22) |
| Biological dust | 1.05 (1.02–1.07) | 1.00 (0.97–1.03) | 0.12 (0.00–0.58) | 0.02 (0.00–4.70) |
* Adjusted for age, sex, PM2.5, ethnicity, Townsend deprivation index, BMI, dietary changes, physical activity, paternal history of diabetes. ** Adjusted for age, sex, PM2.5, Townsend deprivation index, dietary changes, physical activity, paternal history of dementia. *** Significant associations in bold.