Fig. 5.

Docked poses of compound 6f (stick figure) with SARS-CoV-2 (COVID-19) main protease (PDB ID: 6XFN) (A) Protein backbone-ligand interactions; (B) Docked pose of ligand 6f (colour code for ligand: Black-C: White-H; Red-O; Blue-N) conventional hydrogen bonding interactions shown as dashed lines (Green) with 6XFN; (C) Lingard 6f with 6XFN (hydrophobicity surface) at the active binding site; (D) 2D view of interaction type of ligand 6f with surrounding amino acids of 6XFN. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)