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Anti-tuberculosis activity of synthesized compounds against M. tuberculosis by MHB method.
| MICa |
||
|---|---|---|
| Comps | Mg/L | µM |
| 3a | >128 | 353.9 |
| 3b | 64 | 66.2 |
| 3c | >128 | 344.8 |
| 3d | >128 | 336.5 |
| 4a | >128 | 359.8 |
| 4b | 64 | 63.5 |
| 4c | >128 | 322.1 |
| 4d | 128 | 298.5 |
| 5a | 4 | 11.2 |
| 5b | 4 | 13.7 |
| 5c | 8 | 20.8 |
| 5d | 64 | 54.8 |
| 5e | 4 | 12.8 |
| 5f | 4 | 13.2 |
| 5g | 8 | 21.2 |
| 5h | 16 | 53.7 |
| 6a | 2 | 5.9 |
| 6b | 1 | 2.6 |
| 6c | 4 | 12.6 |
| 6d | 8 | 20.6 |
| 6e | 1 | 2.9 |
| 6f | 4 | 14.5 |
| 6g | 8 | 21.6 |
| 6h | 16 | 58.4 |
| Rifampicin | 0.125 | - |
Minimum inhibition concentration (MIC) against H37Rv strain M. tuberculosis (ATCC 27294).
