Table 1: Lectins used in this study and their major specificities |
Acronym
|
Source
|
Major spe cificity
|
GNA |
Galanthus nivalis Snowdrop |
Nonreducing terminal α-D-mannose, especially the mannosyl a1,3-mannose linkage |
NPA |
Narcissus pseudonarcissus Daffodil |
a1,6-Mannose |
HHA |
Hippeastrum hybrid Amaryllis |
a1,3 and a1,6-Mannose |
CON A |
Canavalia ensiformis Jackbean |
a-D-glucosyl and a-D-mannosyl (terminal or 1,2 linked) in high mannose, internediate and small complex N-linked sequences |
PSA |
Pisum sativum Garden Pea |
a-D-mannose in non-bisected bi/tri-antennary, complex N-linked sequences |
LCA |
Lens culinaris Lentil |
Similar to, but not identical with PSA |
e-PHA |
Phaseolus vulgaris (erythroagglutinin) Kidney Bean |
Bi/tri-antennary bisected complex N-linked sequences |
l-PHA |
Phaseolus vulgaris (leukoagglutinin) Kidney Bean |
Tri/tetra-antennary, non- bisected complex N-linked sequences |
BSA-II |
Bandeiraea simplicifolia Griffonia |
Terminal a and βGlcNAca1,3 > a1,6 or β1,3 >> β1,6 |
LEA |
Lycopersicon esculentum Tomato |
β1,4GlcNAc oligomers |
ECA |
Erythrina cristagalli Coral Tree |
Gal β1,4GlcNAc β1- |
AHA |
Arachis hypogaea Peanut |
Gal β1,3GalNAc β1- >Gal β1,4GlcNAc β1- |
MPA |
Maclura pomifera Osage orange |
Gal β1,3GalNAca1- >GalNAcα1- |
HPA |
Helix pomatia Roman snail |
Terminal GalNAca1- |
SBA |
Glycine max Soybean |
Terminal GalNAca1- >Gala1 |
VVA |
Vicia villosa Hairy vetch |
GalNAca1-Ser/Thr and GalNAca1,3Gal β1- |
WFA |
Wisteria floribunda Wisteria |
GalNAca1,6Gal β1- >GalNAca1,3Gal β1- |
DBA |
Dolichos biflorus Horse Gram |
GalNAca1,3(LFuca1,2)Gal- β1,3/4GlcNAc β1- |
UEA-1 |
Ulex europaeus-1 Gorse |
H type 2 antigen (aL-Fuc(1,2)- Gal β1,4GlcNAc β1-) and Ley
|
LTA |
Tetragonolobus purpureus Lotus |
L-fucosyl terminals (especially where clustered), Fuca1,6GlcNAc >Fuca1,2-Gal β1,4(Fuca1,3)-GlcNAc β, Lex,y
|
AAA |
Anguilla anguilla Eel |
H type 1 antigen, Lea
|
BSA-1B4
|
Bandeiraea simplicifolia Griffonia |
Gala1,3Gal β1,4GlcNAc β1- |
SNA-1 |
Sambucus nigra Elderberry Bark |
NeuNAca2,6Gal/GalNAc- |
PTL-1 |
Psophocarpus tetragonolobus Winged bean |
αGalNAc |
PTL-11 |
Psophocarpus tetragonolobus Winged bean |
βGalNAc, H type 1 antigen, Galβ1-3GalNAcαSer/Thr |
MAA |
Maackia amurensis |
NeuNAca2,3Galβ1- |
PAA |
Phytolacca americana Pokeweed |
Poly-N-acetyllactosamine, GlcNAc oligomers |
s-WGA |
Succinylated-Triticum vulgaris Wheatgerm |
N-acetylglucosamine |