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. 2020 Dec 23;12:13233–13239. doi: 10.2147/CMAR.S285691

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© 2020 Zhou et al.

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Combined indicators to assess the prognosis of patients with head and neck squamous cell carcinoma (HNSCC). (A) The prognostic power of different markers for OS in HNSCC using the C-index. (B and C) Kaplan–Meier analysis of the overall survival of patients. (B) HIF-1α⁺ or HIF-1α⁻ status combined with PD-L1⁺ or PD-L1⁻ tumor cells (TC-PD-L1). (C) CD8⁺ TIL or CD8⁻TIL status combined with programmed death ligand 1 (PD-L1)⁺ or PD-L1⁻ tumor microenvironment cells (TMC-PD-L1). Significant differences were evaluated using a Log rank test.