Fig. 2.

PPARδ is not required in the neuroretina for development or maintenance of retinal structure. (A–B) Quantification of the outer nuclear layer (ONL) thickness, representing the thickness of the photoreceptor nuclear layer, at 125 μm intervals from the optic nerve head to 500 μm in the inferior and superior directions at 6 weeks (A) and 12 months (B) of age in Pparδ^fl/fl (WT, black) and Chx10Cre Pparδ^fl/fl (KO, red). Multiple t-tests, P ≥ 0.12, n = 4 of each genotype at 6 weeks and n = 3 WT and 4 KO at 12 months. (C–D) Representative OCT images from Pparδ^fl/f (WT, top) and Chx10Cre Pparδ^fl/fl (KO, bottom) at 6 weeks (C) and 12 months (D) of age. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)