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. 2020 Aug 25;37:101700. doi: 10.1016/j.redox.2020.101700

Fig. 3.

Fig. 3

PPARδ is not required in the neuroretina for development or maintenance of retinal function. (A–B) Photoreceptor function (a-wave) of Chx10Cre Pparδfl/fl KO and WT mice at 6 weeks (A) and 12 months (B) of age under scotopic stimulation conditions. (C–D) Inner retinal function (b-wave) at 6 weeks (C) and 12 months (D) of age under scotopic stimulation conditions. Two-way ANOVA, P ≥ 0.39, n = 15 WT and 13 KO at 6 weeks and n = 3 KO and 5 WT at 12 months. (E–F) Cone photoreceptor function (a-wave) measured by Flicker ERG at 6 weeks (E) and 12 months (F) of age under flicker ERG stimulation conditions. (G–H) Inner retinal function (b-wave) at 6 weeks (G) and 12 months (H) of age. Two-way ANOVA with multiple comparisons, P ≥ 0.15, n = 15 WT and 12 KO for 6 weeks and n = 8 WT and 4 KO for 12 months, plotted error represents standard error of the mean (SEM).