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MOTS-c localization and cytoprotection in RPE cells. (A). Mitochondrial localization of MOTS-c. MOTS-c (green), mitochondria (Red), and nucleus (Blue). (B). Dose-dependent inhibition of oxidative stress-induced cell death by MOTS-c determined by TUNEL assay. Scale Bar: 50 μm. (Sreekumar, PG et al. unpublished data). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)
