Fig. 7.

Bone marrow TTP deficiency had no effects on atherosclerosis after 12 weeks of Western diet feeding in LDLR^−/−mice. (A) The lesion area of the frozen sections were detected by H&E staining and quantified by Image-ProPlus 6.0. The quantitative analysis and representative images are shown. (b) Lipid contents in the aortic lesions were determined by ORO staining. Quantitative analysis and representative images are shown. (C) The areas of macrophages in the aortic root lesions were determined by immunostaining for MOMA-2 (a macrophage marker). Quantitative analysis and representative images are shown. (D) Collagen percentage in the aortic root lesions were determined by trichrome staining. Quantitative analysis and representative images are shown. Data were presented as the mean ± SEM (N = 9 mice per group). Scale bar 100 μm.