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. 2020 Dec 14;11:610963. doi: 10.3389/fimmu.2020.610963

Table 2.

Results of multiple linear regression analysis of immunohistochemistry and histochemistry data from Experiment 1.

Marker Effect of duration of induction Effect of platelet depletion R2 value
CD41+ platelets ↑↑↑ ↓↓↓ 0.54
CD68+ macrophages ↑↑↑ ↓↓↓ 0.36
CD163+ macrophages ↑↑↑ ↓↓↓ 0.41
iNOS+ macrophages 0.09
TSLP ↓↓↓ 0.38
FOXP3+ Tregs ↑↑ ↓↓↓ 0.50
T-bet+ Th1 cells ↑↑↑ ↓↓ 0.33
GATA-3+ Th2 cells ↑↑↑ ↓↓↓ 0.61
RORγT+ Th17 cells ↓↓↓ 0.26
GARP ↑↑↑ ↓↓↓ 0.78
Extent of lesional fibrosis ↑↑↑ ↓↓↓ 0.44

The symbol “↑” denotes elevation while “↓” denotes reduction. The number of “↑” or “↓” indicates the statistical significance level associated with variable, in which one, two, and three such symbols indicate that the p-value is <0.05, 0.01, and 0.001, respectively. The symbol “—” means no association.