Table 2.
Degree centrality analysis of altered brain regions in functional magnetic resonance imaging in early- and late-onset Parkinson disease patients and sex-and age-matched healthy control subjects*.
| Brain region | Peak MNI coordinates | Voxel size | T-value | ||
|---|---|---|---|---|---|
| X | Y | Z | |||
| EOPD < YC | |||||
| Rolandic_Oper_L | −51 | 0 | 9 | 33 | −4.334 |
| Insula_L | −36 | −27 | 21 | 15 | −4.205 |
| Rolandic_Oper_R | 42 | −9 | 15 | 46 | −4.677 |
| EOPD > YC | |||||
| Frontal_Sup_L | −21 | 63 | 24 | 21 | 4.646 |
| Frontal_Sup_L | −12 | 42 | 45 | 32 | 4.228 |
| Precuneus_L | −3 | −57 | 36 | 31 | 4.355 |
| LOPD > OC | |||||
| Cerebelum_Crus1_R | 24 | −84 | −24 | 21 | 3.995 |
| LOPD < OC | |||||
| Putamen_R | 30 | −6 | 3 | 34 | −4.906 |
| Insula_L | −30 | −21 | 18 | 19 | −4.327 |
| Rolandic_Oper_R/Postcentral Gyrus | 45 | −21 | 24 | 25 | −4.293 |
| Rolandic_Oper_L/Postcentral Gyrus | −51 | −12 | 15 | 17 | −4.442 |
| Cingulum_Mid_R | 6 | −9 | 45 | 23 | −5.025 |
MNI, Montreal Neurological Institute. *The p-value was < 0.001 and voxel size was larger >15 (p < 0.05, AlphaSim-corrected).