Table 3.

Changes of auxologic and metabolic parameters of women with TS per month without therapy (age-related increase), growth hormone treatment, hormone replacement therapy.

Parameters [per month]	Age-related increase	p	hGH-related effects	p	HRT-related effects	P
HbA1c [%]	-0.001	ns	+0.001	ns	+0.003	Ns
Insulin [mIE/l]	+0.116	ns	+0.206	0.003	-0.143	0.039
HOMA-IR	+0.022	ns	+0.054	0.006	0.000	ns
Cholesterol [mg/dl]	-0.058	0.004	-0.206	0.006	+0.200	ns
LDL-C [mg/dl]	+0.008	ns	-0.216	0.004	+0.310	0.020
HDL-C [mg/dl]	-0.078	ns	+0.095	0.048	+0.037	ns
TG [mg/dl]	-0.183	ns	+0.322	ns	+0.402	ns

Data were analyzed by linear mixed model and are reported as mean ± SEM. Statistical significance was defined by p-values < 0.05. ns: non-significant.