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. 2020 Dec 14;11:603144. doi: 10.3389/fgene.2020.603144

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Copyright © 2020 Lin, Tang, Zhao, Zhao, Zhang, Wei and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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MiR-144 targets FoxO1 by binding in its 3′UTR. (A) The Venn diagram of target genes prediction data. (B) Top 20 KEGG enrichment that predicted genes by Venn diagram. Dot means genes number, and the color means P-value. (C) Conservation estimation of mature miR-144 sequences within different species. (D) Conservation estimation of miRNA response elements (MREs) between human, mouse, and pig. (E) The location of miR-144 MREs in porcine FoxO1 gene 3′UTR. (F) The results of dual fluorescence activity detection of miR-144 targeting FoxO1. **p < 0.01.