TABLE 6.

Multivariable linear regression analysis of clinical factors associated with MMSE score at year 2.

Predictors	Beta	P value
Gender (male)	0.083	0.179
Age	−0.062	0.001
Disease duration	−0.072	0.267
Education levels	−0.019	0.755
Olfactory function (olfactory dysfunction)	−0.792	0.023
H-Y stage	−0.053	0.484
UPDRS III score at baseline	−0.026	0.043
MMSE score at baseline	0.578	<0.001

Values in bold refer to statistically significant differences (P < 0.05). H-Y, Hoehn and Yahr; MMSE, Mini-Mental State Examination; UPDRS, Unified Parkinson’s Disease Rating Scale.