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. 2020 Dec 14;7:576298. doi: 10.3389/fmolb.2020.576298

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Copyright © 2020 Chen, Huang, Wang, Zhan and Quan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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WGCNA and module selection. (A,C) Sample dendrogram and trait heatmaps with metastasis, MA, and Th2 of TARGET-OS (A) and GSE21257 (C). In metastasis-trait, red represents patients with metastasis and white represents without metastasis; in MA and Th2-traits, the red or blue deeper, the positive or negative NESs higher. (B,D) Cluster dendrograms in TARGET-OS (B) and GSE21257 (D). (E,F) Heatmaps of module–trait relationships between gene modules and traits of metastasis, MA, and Th2 in TARGET-OS (E) and GSE21257 (F). The number in brackets on the right of each cell is the P-value, and the number on the left is the correlation coefficient.