The RFS curves of patients who underwent LT with or without bridging or downstaging for HCC, stratified by initial OPTN stage and status after LRT: initial OPTN stage T1 or T2 (a) and initial OPTN stage T3 (b). RFS, recurrence-free survival; LT, liver transplantation; HCC, hepatocellular carcinoma; OPTN, Organ Procurement and Transplantation Network; LRT, locoregional therapy; SD, successful downstaging; DF, downstaging failure.