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. 2020 Nov 4;7(6):ENEURO.0451-19.2020. doi: 10.1523/ENEURO.0451-19.2020

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Copyright © 2020 Grace and Horner

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 3. — Effects of vlPAG/DpMe inhibition on sleep macroarchitecture and bistability. A, Effects of vlPAG/DpMe inhibition on the levels of sleep-wake states as a proportion of the TRT. Levels of REM sleep are given for both 3-stage scoring and 4-stage NRt scoring. B, Effects of vlPAG/DpMe inhibition on the levels of REM sleep and NRt states as a proportion of the TST. Levels of REM sleep are given for both 3-stage scoring and 4-stage NRt scoring. For each comparison, the paired mean differences are shown in Cumming estimation plots. The raw data are plotted on the upper axes; each paired set of observations is connected by a line. On the lower axes, each paired mean difference is plotted as a bootstrap sampling distribution. Mean differences are depicted as dots; 95% CIs are indicated by the ends of the vertical error bars.