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. 2020 Dec 23;7(6):ENEURO.0202-20.2020. doi: 10.1523/ENEURO.0202-20.2020

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Copyright © 2020 Lyon et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 8. — Drd2-Pet1 neuron electrophysiological properties in male versus female mice. Membrane and AP characteristics were analyzed in GFP-marked Drd2-Pet1 male and female neurons using whole-cell patch-clamp electrophysiology in acute brain slices from triple transgenic Drd2-Cre;Pet1-Flpe;RC-FrePe mice. Membrane potential (A), membrane resistance (B), AP threshold (C), AP amplitude (D), and AHP amplitude (F) do not differ in male (n = 19) or female (n = 44) Drd2-Pet1 neurons while (E) male Drd2-Pet1 neurons had a significantly longer (2.847 ± 0.155 ms, n = 19 cells) AP duration than in females (2.54 ± 0.094 ms, n = 44 cells, p = 0.0275, unpaired t test).