Table 2.
PI-RADS 3 lesion characteristics.
| Total PI-RADS 3 Lesions (n = 525) | PI-RADS 3 Lesions Düsseldorf (n = 363) | PI-RADS 3 Lesions Rotterdam (n = 162) | p Value | |
|---|---|---|---|---|
| Lesion size (largest diameter, mm), median (IQR) | 11 (9–13) | 12 (10–13) | 10 (7–12) | <0.001 |
| Lesion zone, no. (%) | ||||
| Peripheral zone | 186 (35) | 107 (30) | 79 (49) | <0.001 |
| Transition zone | 324 (62) | 246 (68) | 78 (48) | |
| Central zone | 2 (1) | 0 (0) | 2 (1) | |
| >1 zone | 13 (3) | 10 (3) | 3 (2) | |
| Lesion location, no. (%) | ||||
| Anterior | 340 (65) | 258 (71) | 82 (51) | <0.001 |
| Posterior | 178 (34) | 103 (28) | 75 (46) | |
| Both | 7 (1) | 2 (1) | 5 (3) | |
| Grade at TBx, no. (%) | ||||
| no PCa | 417 (79) | 346 (95) | 71 (44) | <0.001 |
| G 1 | 65 (12) | 10 (3) | 55 (34) | |
| G 2 | 23 (4) | 5 (1) | 18 (11) | |
| G 2 with CR and/or IDC | 10 (2) | 0 (0) | 10 (6) | |
| G 3 | 9 (2) | 2 (1) | 7 (4) | |
| G 4–5 | 1 (1) | 0 (0) | 1 (1) |
IQR: interquartile range; TBx: targeted biopsy; PCa: prostate cancer; G: grade; CR: cribriform growth pattern; IDC: intraductal carcinoma; PI-RADS: Prostate Imaging Reporting and Data System.