Table 2.
Weighted adjusted * analysis model estimates for the association between PFAS and thyroid hormones (n = 1325).
| Ln TSH (mIU/L) | Ln Total T4 (µg/dL) | Ln Free T4 (ng/dL) | Ln Total T3 (ng/dL) | Ln Free T3 (pg/mL) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| PFAS | Badj * (95% CI) | p-Value | Badj * (95% CI) | p-Value | Badj * (95% CI) | p-Value | Badj * (95% CI) | p-Value | Badj * (95% CI) | p-Value |
| Ln PFOA (µmol/L) | 0.006 (−0.041; 0.053) | 0.787 | −0.008 (−0.027; 0.012) | 0.411 | 0.007 (−0.007; 0.021) | 0.311 | 0.011 (−0.009; 0.031) | 0.252 | 0.003 (−0.011; 0.018) | 0.612 |
| Ln PFOS (µmol/L) | −0.002 (−0.055; 0.051) | 0.943 | −0.010 (−0.024; 0.004) | 0.138 | 0.021 (0.008; 0.035) | 0.003 | 0.001 (−0.015; 0.017) | 0.873 | 0.002 (−0.006; 0.010) | 0.565 |
| Ln PFHxS (µmol/L) | 0.002 (−0.036; 0.040) | 0.899 | −0.005 (−0.023; 0.013) | 0.558 | 0.011 (−0.003; 0.025) | 0.127 | 0.010 (−0.006; 0.026) | 0.198 | −0.001 (−0.015; 0.012) | 0.834 |
| Ln PFNA (µmol/L) | −0.005 (−0.050; 0.041) | 0.837 | 0.000 (−0.019; 0.020) | 0.968 | 0.021 (0.005; 0.038) | 0.014 | 0.013 (−0.006; 0.032) | 0.174 | 0.012 (0.002; 0.023) | 0.024 |
| Ln total PFAS (µmol/L) | −0.004 (−0.056; 0.049) | 0.883 | −0.010 (−0.027; 0.007) | 0.216 | 0.023 (0.009; 0.038) | 0.004 | 0.003 (−0.014; 0.020) | 0.716 | 0.003 (−0.008; 0.014) | 0.613 |
* Adjusted for sex, race, age group, BMI group, iodine status and smoking status (questionnaire); CI: confidence interval, Ln: Natural log transformed; Bold means significant.