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. 2020 Nov 27;8(4):708. doi: 10.3390/vaccines8040708

Figure 2.

Figure 2

Alternative bispecific antibody formats in clinical development. Legend: (A) immunoglobulin gamma (IgG)-like bispecific antibody (bsAb); (B) bispecific fusion protein; (C) IgG with additional antigen binding moiety; (D) bsAb conjugates; (E) bsAb fragments including bispecific T-cell engagers (BiTE), dual-affinity re-targeting antibody (DART), and tandem diabody (TandAb). Dark and light colours represent heavy and light chains, respectively; blue and red colours represent variable fragments specific for different antigens.