Table 7.

Medications prescribed and their treatment profile [56,57].

Medications	Weight Profile
Antidiabetes	GLP-1 analogs (eg, exenatide, albiglutide, dulaglutide, semaglutide and liraglutide) or SGLT-2 inhibitors (dapagliflozin, empagliflozin and canagliflozin) promote weight loss Basal insulin causes less weight gain than other insulin types
Antihypertensives	Angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and calcium channel blockers should be preferred over β-adrenergic blockers which cause weight gain
Antidepressants	Paroxetine, amitryiptyline, mirtazapine, and nortriptyline are linked to weight gain Bupropion causes weight loss
Antipsychotics	Clozapine and olanzapine have a greater likelihood for weight gain, while ziprasidone appears to have the lowest risk for weight gain
Antiepileptics	Felbamate, topiramate and zonisamide may be preferred over other antiepileptics as they cause weight loss
Antihistamines	Choose one with less sedation
Antiretroviral	Most antiretrovirals cause weight gain, weight monitoring is important