Table A1.
Correlations between the change scores of the Montreal Cognitive Assessment Domain Scores (MoCA-DS), Total Score (MoCA-TS) and Memory Index Score (MoCA-MIS), and the change scores of the Patient Competency Rating Scale domain scores (PCRS-DS) and Total Score (PCRS-TS) between the sixth week of admission (T1) and at clinical discharge (T2) for the patient (a) and clinician (b) ratings for the total sample and split per group.
| (a) Patient rating | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Total (n = 287) | AUD (n = 51) | ARCI (n = 149) | KS (n = 87) | |||||||||||||||||
| MoCA | PCRS | PCRS | PCRS | PCRS | ||||||||||||||||
| ADL | CO | IP | EM | TS | ADL | CO | IP | EM | TS | ADL | CO | IP | EM | TS | ADL | CO | IP | EM | TS | |
| EF | −0.02 (0.395) | −0.01 (0.448) | −0.03 (0.294) | 0.01 (0.418) | −0.01 (0.413) | −0.04 (0.399) | −0.15 (0.155) | −0.15 (0.152) | −0.31 (0.013)* | −0.22 (0.065) | −0.02 (0.408) | −0.06 (0.234) | −0.06 (0.232) | −0.00 (0.848) | −0.04 (0.296) | 0.00 (0.496) | 0.14 (0.107) | 0.07 (0.251) | 0.18 (0.047)* | 0.12 (0.130) |
| VA | 0.15 (0.006)* | 0.05 (0.190) | 0.03 (0.314) | 0.01 (0.436) | 0.08 (0.100) | 0.13 (0.190) | −0.06 (0.330) | −0.16 (0.131) | −0.17 (0.110) | −0.08 (0.282) | 0.19 (0.011)* | 0.11 (0.087) | 0.05 (0.294) | 0.00 (0.496) | 0.11 (0.098) | 0.09 (0.211) | −0.01 (0.482) | 0.05 (0.315) | 0.07 (0.251) | 0.06 (0.283) |
| ACW | 0.05 (0.179) | 0.12 (0.019)* | 0.07 (0.124) | 0.09 (0.069) | 0.11 (0.038)* | 0.06 (0.328) | 0.02 (0.450) | −0.02 (0.445) | −0.03 (0.426) | 0.02 (0.455) | −0.02 (0.425) | 0.11 (0.101) | 0.07 (0.209) | 0.10 (0.104) | 0.08 (0.167) | 0.17 (0.062) | 0.20 (0.034)* | 0.11 (0.154) | 0.11 (0.159) | 0.19 (0.042)* |
| L | 0.08 (0.088) | 0.08 (0.101) | 0.12 (0.018)* | 0.03 (0.320) | 0.09 (0.056) | 0.19 (0.088) | −0.11 (0.230) | 0.02 (0.454) | −0.22 (0.061) | −0.04 (0.401) | 0.04 (0.304) | 0.09 (0.131) | 0.10 (0.107) | 0.04 (0.307) | 0.09 (0.151) | 0.11 (0.158) | 0.13 (0.119) | 0.24 (0.012)* | 0.12 (0.132) | 0.18 (0.047)* |
| AR | −0.03 (0.326) | 0.09 (0.062) | −0.02 (0.390) | −0.01 (0.443) | 0.02 (0.388) | −0.13 (0.182) | −0.12 (0.210) | −0.14 (0.170) | −0.13 (0.187) | −0.18 (0.109) | 0.06 (0.239) | 0.19 (0.011)* | 0.05 (0.272) | 0.10 (0.124) | 0.12 (0.068) | −0.17 (0.062) | −0.05 (0.317) | −0.10 (0.171) | −0.16 (0.067) | −0.15 (0.085) |
| M | 0.06 (0.172) | 0.00 (0.499) | −0.02 (0.382) | −0.03 (0.334) | 0.01 (0.464) | 0.09 (0.259) | −0.13 (0.184) | −0.19 (0.090) | −0.31 (0.013)* | −0.17 (0.111) | 0.09 (0.138) | 0.03 (0.376) | 0.03 (0.339) | 0.04 (0.332) | 0.06 (0.251) | −0.08 (0.229) | −0.02 (0.414) | −0.05 (0.325) | −0.00 (0.490) | −0.05 (0.327) |
| O | 0.12 (0.024)* | 0.12 (0.021)* | 0.09 (0.073) | 0.07 (0.124) | 0.12 (0.019)* | 0.07 (0.323) | −0.24 (0.045)* | −0.31 (0.013)* | −0.11 (0.217) | −0.20 (0.079) | 0.11 (0.092) | 0.14 (0.047)* | 0.06 (0.240) | 0.11 (0.095) | 0.13 (0.062) | 0.17 (0.063) | 0.21 (0.026)* | 0.25 (0.009)* | 0.09 (0.204) | 0.22 (0.019)* |
| TS | 0.15 (0.006)* | 0.14 (0.009)* | 0.08 (0.089) | 0.05 (0.184) | 0.13 (0.012)* | 0.12 (0.198) | −0.19 (0.087) | −0.25 (0.039)* | −0.36 (0.005)* | −0.22 (0.060) | 0.17 (0.019)* | 0.20 (0.007)* | 0.11 (0.087) | 0.13 (0.061) | 0.19 (0.011)* | 0.14 (0.101) | 0.22 (0.022)* | 0.23 (0.018)* | 0.15 (0.080) | 0.23 (0.017)* |
| MIS | 0.04 (0.272) | 0.06 (0.172) | 0.01 (0.437) | 0.02 (0.400) | 0.04 (0.260) | 0.10 (0.241) | −0.16 (0.129) | −0.23 (0.052) | −0.35 (0.006)* | −0.21 (0.073) | 0.02 (0.400) | 0.02 (0.403) | 0.03 (0.341) | 0.03 (0.379) | 0.03 (0.359) | 0.03 (0.405) | 0.19 (0.043)* | 0.05 (0.318) | 0.12 (0.135) | 0.12 (0.125) |
| (b) Clinician rating | ||||||||||||||||||||
| Total (n = 297) | AUD (n = 52) | ARCI (n = 154) | KS (n = 91) | |||||||||||||||||
| MoCA | PCRS | PCRS | PCRS | PCRS | ||||||||||||||||
| ADL | CO | IP | EM | TS | ADL | CO | IP | EM | TS | ADL | CO | IP | EM | TS | ADL | CO | IP | EM | TS | |
| EF | 0.06 (0.151) | 0.12 (0.023)* | 0.05 (0.186) | 0.09 (0.060) | 0.10 (0.040)* | −0.04 (0.398) | −0.03 (0.423) | 0.01 (0.479) | 0.14 (0.164) | 0.03 (0.418) | 0.08 (0.174) | 0.16 (0.026)* | 0.07 (0.206) | 0.04 (0.311) | 0.11 (0.091) | 0.09 (0.204) | 0.12 (0.123) | 0.06 (0.304) | 0.14 (0.092) | 0.14 (0.101) |
| VA | 0.12 (0.022)* | 0.20 (<0.001)*** | 0.07 (0.116) | 0.13 (0.011)* | 0.17 (0.002)** | 0.10 (0.244) | 0.22 (0.057) | 0.03 (0.415) | 0.27 (0.029)* | 0.20 (0.074) | 0.15 (0.033)* | 0.19 (0.009)* | 0.13 (0.049)* | 0.20 (0.006)* | 0.21 (0.005)** | 0.07 (0.272) | 0.21 (0.022)* | −0.04 (0.370) | −0.07 (0.272) | 0.06 (0.283) |
| ACW | 0.12 (0.020)* | 0.12 (0.017)* | 0.07 (0.105) | 0.01 (0.407) | 0.10 (0.036)* | 0.18 (0.099) | −0.06 (0.346) | 0.10 (0.233) | 0.13 (0.182) | 0.11 (0.210) | 0.11 (0.096) | 0.18 (0.014)* | 0.05 (0.254) | −0.04 (0.293) | 0.10 (0.118) | 0.12 (0.129) | 0.10 (0.178) | 0.09 (0.200) | 0.05 (0.321) | 0.12 (0.136) |
| L | 0.08 (0.082) | 0.13 (0.015)* | 0.03 (0.277) | −0.01 (0.445) | 0.08 (0.097) | 0.13 (0.183) | 0.08 (0.300) | −0.22 (0.056) | −0.13 (0.173) | −0.05 (0.354) | 0.11 (0.086) | 0.21 (0.004)** | 0.20 (0.007)* | 0.03 (0.361) | 0.17 (0.016)* | 0.03 (0.408) | 0.02 (0.419) | −0.08 (0.226) | 0.03 (0.388) | −0.00 (0.500) |
| AR | 0.02 (0.359) | 0.14 (0.008)* | 0.16 (0.003)** | 0.08 (0.085) | 0.13 (0.013)* | −0.11 (0.223) | −0.03 (0.417) | 0.01 (0.470) | 0.02 (0.441) | −0.03 (0.410) | 0.02 (0.392) | 0.10 (0.099) | 0.14 (0.040)* | 0.04 (0.302) | 0.10 (0.116) | 0.09 (0.198) | 0.31 (0.001)** | 0.30 (0.002)** | 0.22 (0.018)* | 0.31 (0.002)** |
| M | 0.08 (0.084) | 0.04 (0.265) | −0.02 (0.385) | −0.02 (0.352) | 0.02 (0.338) | 0.32 (0.011)* | 0.11 (0.225) | 0.00 (0.497) | 0.16 (0.129) | 0.19 (0.091) | 0.04 (0.299) | 0.03 (0.356) | −0.04 (0.307) | −0.05 (0.251) | −0.01 (0.477) | 0.02 (0.421) | 0.03 (0.391) | 0.07 (0.266) | −0.04 (0.338) | 0.02 (0.44) |
| O | 0.21 (<0.001)*** | 0.21 (<0.001)*** | 0.16 (0.003)** | 0.15 (0.005)* | 0.23 (<0.001)*** | 0.17 (0.110) | 0.10 (0.244) | −0.00 (0.498) | 0.20 (0.279) | 0.15 (0.139) | 0.16 (0.028)* | 0.18 (0.013)* | 0.11 (0.081) | −0.01 (0.451) | 0.14 (0.044)* | 0.30 (0.002)** | 0.30 (0.002)** | 0.28 (0.004)** | 0.32 (0.001)** | 0.39 (<0.001)*** |
| TS | 0.23 (<0.001)*** | 0.30 (<0.001)*** | 0.16 (0.004)** | 0.13 (0.015)* | 0.26 (<0.001)*** | 0.25 (0.039)* | 0.12 (0.192) | −0.02 (0.456) | 0.21 (0.069) | 0.18 (0.097) | 0.22 (0.003)** | 0.33 (<0.001)*** | 0.20 (0.008)* | 0.06 (0.242) | 0.25 (<0.001)*** | 0.25 (0.008)* | 0.36 (<0.001)*** | 0.21 (0.022)* | 0.21 (0.022)* | 0.34 (<0.001)*** |
| MIS | 0.08 (0.085) | 0.02 (0.377) | −0.01 (0.465) | −0.03 (0.323) | 0.02 (0.365) | 0.21 (0.064) | 0.07 (0.309) | −0.01 (0.474) | 0.18 (0.101) | 0.15 (0.148) | −0.00 (0.496) | −0.05 (0.263) | −0.08 (0.171) | −0.06 (0.224) | −0.06 (0.235) | 0.18 (0.047)* | 0.14 (0.097) | 0.13 (0.108) | −0.05 (0.330) | 0.13 (0.113) |
Note: AUD = Alcohol Use Disorder; ARCI = Alcohol-Related Cognitive Impairments; KS=Korsakoff’s Syndrome; ADL = Activities of Daily Living; CO=Cognitive abilities; IP=Interpersonal abilities; EM = Emotional lability; TS = Total Score; EF = Executive Functioning; VA = Visuospatial Abilities; ACW = Attention, Concentration and Working memory; L = Language; AR = Abstract Reasoning; M = Memory; O=Orientation.
* P < 0.05;
* * P < 0.005;
* * * P < 0.001.