Table 2.
Means and SDs of the Montreal Cognitive Assessment Domain Scores (MoCA-DS) on all three assessment points for the total sample and split per group. Post hoc comparison gives a description of the direction of significant differences between groups (column), between assessments (row) and the interaction between groups and assessments (in italics)
| Cognitive domain (range) | Total | AUD | ARCI | KS | P-value | Post hoc comparison |
|---|---|---|---|---|---|---|
| (n = 166) | (n = 35) | (n = 82) | (n = 49) | |||
| Executive functioning (0–2) | 0.024* | AUD > KS† | ||||
| T0 | 0.66 (0.69) | 0.77 (0.73) | 0.65 (0.71) | 0.61 (0.64) | ||
| T1 | 1.02 (0.68) | 1.17 (0.71) | 1.05 (0.70) | 0.88 (0.60) | ||
| T2 | 1.18 (0.74) | 1.43 (0.66) | 1.21 (0.73) | 0.96 (0.76) | ||
| P-value | <0.001*** | 0.499 | ||||
| Post hoc comparison | T0 < T1; T0 < T2; T1 < T2†† | |||||
| Visuospatial abilities (0–4) | 0.066 | |||||
| T0 | 1.97 (1.04) | 2.20 (1.05) | 1.87 (1.00) | 1.98 (1.09) | ||
| T1 | 2.39 (1.07) | 2.63 (0.91) | 2.29 (1.06) | 2.37 (1.17) | ||
| T2 | 2.40 (0.98) | 2.74 (0.74) | 2.41 (1.01) | 2.12 (1.01) | ||
| P-value | <0.001*** | 0.271 | ||||
| Post hoc comparison | T0 < T1;T0 < T2†† | |||||
| Attention (0–6) | 0.063 | |||||
| T0 | 5.00 (1.24) | 5.29 (0.99) | 4.85 (1.30) | 5.04 (1.27) | ||
| T1 | 5.17 (1.12) | 5.31 (1.02) | 5.01 (1.22) | 5.35 (0.99) | ||
| T2 | 5.32 (1.01) | 5.51 (0.82) | 5.13 (1.16) | 5.49 (0.79) | ||
| P-value | 0.005*,††† | 0.819 ††† | ||||
| Post hoc comparison | T0 < T2†† | |||||
| Language (0–5) | 0.538 | |||||
| T0 | 4.07 (0.89) | 4.23 (0.77) | 3.96 (0.87) | 4.14 (1.00) | ||
| T1 | 3.36 (1.01) | 3.51 (1.17) | 3.35 (1.04) | 3.27 (0.84) | ||
| T2 | 3.51 (0.64) | 3.51 (0.66) | 3.50 (0.69) | 3.53 (0.54) | ||
| P-value | <0.001***,††† | 0.440 ††† | ||||
| Post hoc comparison | T0 > T1; T0 > T2†† | |||||
| Abstract reasoning (0–2) | 0.562 | |||||
| T0 | 1.15 (0.78) | 1.20 (0.80) | 1.11 (0.75) | 1.18 (0.81) | ||
| T1 | 1.29 (0.75) | 1.37 (0.69) | 1.20 (0.78) | 1.39 (0.73) | ||
| T2 | 1.66 (0.57) | 1.57 (0.66) | 1.68 (0.54) | 1.69 (0.55) | ||
| P-value | <0.001***,††† | 0.513 ††† | ||||
| Post hoc comparison | T0 < T2; T1 < T2†† | |||||
| Memory (0–5) | <0.001*** | AUD > ARCI; AUD > KS; ARCI>KS†††† | ||||
| T0 | 1.37 (1.57) | 2.37 (1.82) | 1.51 (1.43) | 0.41 (1.02) | ||
| T1 | 1.66 (1.74) | 3.37 (1.48) | 1.83 (1.57) | 0.14 (0.41) | ||
| T2 | 1.87 (1.77) | 3.23 (1.61) | 2.17 (1.60) | 0.41 (0.96) | ||
| P-value | 0.001**,††† | 0.005* ,††† | ||||
| Post hoc comparison | T0 < T1; T0 < T2†† | |||||
| Orientation (0–6) | <0.001*** | AUD > ARCI; AUD > KS; ARCI>KS†††† | ||||
| T0 | 4.43 (1.72) | 5.63 (0.73) | 4.80 (1.40) | 2.94 (1.70) | ||
| T1 | 5.01 (1.27) | 5.69 (0.63) | 5.50 (0.79) | 3.69 (1.31) | ||
| T2 | 5.04 (1.35) | 5.66 (0.64) | 5.56 (0.76) | 3.73 (1.58) | ||
| P-value | <0.001***,††† | 0.052 ††† | ||||
| Post hoc comparison | T0 < T1; T0 < T2†† |
Note: AUD = Alcohol Use Disorder; ARCI = Alcohol-Related Cognitive Impairments; KS=Korsakoff’s Syndrome; T0 = baseline/intake; T1 = after 6 weeks of clinical admission; T2 = at clinical discharge.
†Bonferroni.
††Hochberg’s GT2.
†††Greenhouse–Geisser.
††††Games-Howell.
* P < 0.05;
* * P < 0.005;
* * * P < 0.001.