Table 3.
(a) Patient rating | ||||||
---|---|---|---|---|---|---|
Cognitive domain (range) | Total | AUD | ARCI | KS | P-value | Post hoc comparison† |
(n = 300) | (n = 53) | (n = 153) | (n = 94) | |||
Activities of daily living (8–40) | 0.098 | |||||
T1 | 34.11 (5.50) | 35.38 (5.43) | 33.54 (6.01) | 34.34 (4.50) | ||
T2 | 35.05 (4.45) | 36.15 (3.82) | 34.90 (4.66) | 34.67 (4.38) | ||
P-value | 0.003** | 0.174 | ||||
Cognitive abilities (8–40) | <0.001*** | AUD > ARCI; AUD > KS | ||||
T1 | 31.73 (5.61) | 34.23 (4.55) | 31.54 (5.67) | 30.62 (5.67) | ||
T2 | 32.53 (5.13) | 34.34 (4.46) | 32.84 (5.01) | 30.99 (5.31) | ||
P-value | 0.046* | 0.162 | ||||
Interpersonal abilities (7–35) | 0.131 | |||||
T1 | 27.58 (4.88) | 28.45 (4.51) | 27.24 (5.10) | 27.66 (4.68) | ||
T2 | 27.90 (4.62) | 29.19 (4.22) | 27.63 (4.86) | 27.61 (4.35) | ||
P-value | 0.128 | 0.435 | ||||
Emotional lability (7–35) | 0.679 | |||||
T1 | 24.52 (4.92) | 23.89 (4.67) | 24.43 (4.96) | 25.02 (4.99) | ||
T2 | 25.19 (4.80) | 24.92 (4.83) | 25.31 (4.99) | 25.13 (4.52) | ||
P-value | 0.008* | 0.252 | ||||
Total score (30–150) | 0.130 | |||||
T1 | 117.94 (18.16) | 121.94 (16.50) | 116.75 (19.09) | 117.64 (17.34) | ||
T2 | 120.66 (16.51) | 124.60 (15.20) | 120.69 (16.83) | 118.39 (16.42) | ||
P-value | 0.004** | 0.197 | ||||
(b) Clinician rating | ||||||
Cognitive domain (range) | Total | AUD | ARCI | KS | P-value | Post hoc comparison† |
(n = 348) | (n = 58) | (n = 179) | (n = 111) | |||
Activities of daily living (8–40) | <0.001*** | AUD > ARCI; AUD > KS; ARCI>KS | ||||
T1 | 25.83 (7.22) | 30.98 (5.56) | 28.02 (6.24) | 19.59 (4.94) | ||
T2 | 26.93 (7.37) | 32.34 (5.38) | 29.01 (6.00) | 20.76 (6.07) | ||
P-value | <0.001*** | 0.870 | ||||
Cognitive abilities (8–40) | <0.001*** | AUD > ARCI; AUD > KS; ARCI>KS | ||||
T1 | 24.67 (7.62) | 29.93 (5.75) | 27.53 (6.04) | 17.31 (4.93) | ||
T2 | 26.02 (7.64) | 32.05 (4.59) | 28.57 (5.78) | 18.77 (6.04) | ||
P-value | <0.001*** | 0.435 | ||||
Interpersonal abilities (7–35) | <0.001*** | AUD > KS; ARCI>KS | ||||
T1 | 23.90 (4.63) | 25.43 (4.33) | 24.71 (4.32) | 21.80 (4.59) | ||
T2 | 23.13 (5.24) | 25.29 (5.25) | 23.83 (4.91) | 20.88 (4.99) | ||
P-value | 0.031* | 0.576 | ||||
Emotional lability (7–35) | 0.162 | |||||
T1 | 23.44 (4.37) | 23.29 (4.20) | 23.62 (4.28) | 23.23 (4.65) | ||
T2 | 21.77 (4.77) | 23.16 (4.80) | 21.82 (4.70) | 20.97 (4.74) | ||
P-value | <0.001*** | 0.032 * | AUD: T1 = T2; ARCI: T1 > T2; KS: T1 > T2; T1: AUD = ARCI=KS; T2: AUD > KS | |||
Total score (30–150) | <0.001*** | AUD > ARCI; AUD > KS;ARCI>KS | ||||
T1 | 97.84 (19.67) | 109.61 (16.66) | 103.88 (16.87) | 81.93 (15.09) | ||
T2 | 97.86 (21.18) | 112.84 (17.17) | 103.22 (17.82) | 81.38 (17.56) | ||
P-value | 0.493 | 0.266 |
Note: AUD = Alcohol Use Disorder; ARCI = Alcohol-Related Cognitive Impairments; KS=Korsakoff’s Syndrome; T1 = after 6 weeks of clinical admission; T2 = at clinical discharge.
†Hochberg’s GT2.
* P < 0.05.
* * P < 0.005.
* * * P < 0.001.