Table 2.

Changes in Average Monthly Antimicrobial Use (Days of Therapy per 1000 Patient-days Present) at Intervention and Nonintervention Veterans Affairs Facilities Pre and Postintervention

	Intervention Sites (n = 8)						Nonintervention Sites (n = 118)
Antimicrobial Use	Pre	95% CI	Post	95% CI	% Change	P Value	Pre	95% CI	Post	95% CI	% Change	P Value	% Difference	P Value
Total	533	474–599	522	471–578	−2.1	.25	548	526–572	562	541–583	+2.5	.0026	−4.6	.025
Anti-methicillin-resistant Staphylococcus aureus	102	79–132	91	71–97	−11.3	<.0001	105	97–113	98	91–105	−6.6	<.0001	−5.2	.092
Antipseudomonal	117	96–143	113	92–139	−3.4	.185	133	123–144	138	128–149	+3.6	.011	−7.0	.018

Abbreviation: CI, confidence interval.