Table 1.
Baseline Characteristics
| Patient Characteristics | Full Cohort (n = 58) | Treatment-Naive Patients (n = 34) | Treatment-Experienced Patients (n = 24) |
|---|---|---|---|
| Age, mean (SD) | 65.97 (15.79) | 63.38 (18.41) | 69.62 (10.38) |
| Weight, mean (SD), kg | 59.42 (12.80) | 56.87 (13.13) | 63.04 (11.62) |
| Male sex, no. (%) | 29 (50) | 13 (38) | 16 (67) |
| Cirrhosis, no. (%)a | 25 (43) | 9 (26) | 16 (67) |
| IL28B genotype, no. (%) | |||
| GG | 3 (6) | 2 (7) | 1 (4) |
| TG | 12 (22) | 5 (17) | 7 (29) |
| TT | 35 (65) | 19 (63) | 16 (67) |
| Unknown | 8 (14) | 8 (24) | 0 (0) |
| Baseline HCV load, mean (SD), log IU/mL | 6.50 (0.87) | 6.28 (1.00) | 6.81 (0.52) |
| HCV genotype, no. (%) | |||
| 1B | 29 (50) | 15 (44) | 14 (58) |
| 1B and 2B | 1 (2) | 1 (3) | 0 (0) |
| 2B | 11 (19) | 6 (18) | 5 (21) |
| 2A | 15 (26) | 11 (32) | 4 (17) |
| 3A | 2 (3) | 1 (3) | 1 (4) |
Abbreviations HCV, hepatitis C virus; SD; standard deviation.
aCirrhosis is more common among treatment-experienced than among treatment-naive patients (P < .01).