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YFV infects and destroys human and macaque hepatocytes, but not murine hepatocytes. (A) Low-magnification photographs of serial FFPE liver sections from a moribund hFRG mouse stained brown for FAH using IHC (Left) and YFV RNA using in situ hybridization (ISH) (Right). (B) ISH for YFV RNA in areas of prominent tissue damage in macaques and murine livers, counterstained with hematoxylin (Scale bars, 50 μm.)
