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. 2020 Nov 23;11:573074. doi: 10.3389/fphar.2020.573074

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Copyright © 2020 Yao, Zuo, Deng, Liu, Zhan, Wang, Xu, Ma, and Zhao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Physcion effectively reduce the lipogenesis induced by ethanol. (A) The mRNA expression of Srebp1, Fasn, and Pparα. (B) The protein expression of AMPKα, p-AMPKα, PPARα, and SREBP1. (C) Immunofluorescence staining of SREBP1 (×400 original magnification). (D) The phospho-AMPKα staining (green) and nuclei with DAPI (blue) are shown. Values significantly different from the control are indicated by hash signs (^# p < 0.05). Values significantly different from the ethanol are indicated by asterisks (*p < 0.05).