Table 3.
Absolute values of the inflammatory markers.
Inflammatory markers | SAL | OVA | OVA-RHO inhibitor | OVA-anti-IL17 | OVA-RHO inhibitor-anti-IL17 |
---|---|---|---|---|---|
CD4 (cells/104μm2) | 0.6 ± 1.2 | 5.5 ± 3.2* | 2.6 ± 5.3** | 2.5 ± 5.1*,** | 2.3 ± 4.4** |
CD8 (cells/104μm2) | 11.2 ± 12.0 | 40.8 ± 22.6* | 23.9 ± 17.8** | 14.2 ± 15.1** | 9.2 ± 11.2**,& |
IL-1β (cells/104μm2) | 4.7 ± 5.8 | 35.0 ± 31.2* | 3.9 ± 6.6**,# | 19.1 ± 14.4*,** | 8.5 ± 9.1**,# |
IL-4 (cells/104μm2) | 1.9 ± 3.6 | 9.2 ± 7.4* | 0.6 ± 1.8** | 2.0 ± 3.4** | 0.6 ± 1.8** |
IL-5 (cells/104μm2) | 2.5 ± 3.9 | 14.6 ± 15.3* | 2.9 ± 4.0** | 6.2 ± 8.5** | 1.8 ± 3.5** |
IL-6 (cells/104μm2) | 0.1 ± 0.6 | 5.0 ± 6.2* | 0.5 ± 1.6** | 0.4 ± 1.4** | 0.3 ± 1.2** |
IL-10 (cells/104μm2) | 0.9 ± 1.4 | 7.8 ± 9.9* | 3.5 ± 4.8** | 4.2 ± 5.3** | 3.2 ± 4.4** |
IL-13 (cells/104μm2) | 0.8 ± 1.6 | 6.8 ± 7.4* | 2.6 ± 6.3** | 1.5 ± 3.5** | 2.4 ± 3.8** |
IL-17 (cells/104μm2) | 1.9 ± 2.1 | 12.0 ± 2.8* | 7.2 ± 4.1*,** | 5.3 ± 2.7*,** | 2.9 ± 0.6*,**,& |
TNF-α (cells/104μm2) | 2.7 ± 4.7 | 7.1 ± 5.2* | 1.6 ± 3.4** | 2.3 ± 4.0** | 1.1 ± 2.5** |
IL, interleukin; TNF, tumor necrosis factor; OVA, animals induced to chronic allergic pulmonary inflammation by ovalbumin; OVA-anti-IL17, animals with induction of chronic allergic pulmonary inflammation and use of anti-IL17; OVA-RHO inhibitor, animals with induction of chronic allergic pulmonary inflammation and use of Rho-kinase inhibitor; OVA-RHO inhibitor-anti-IL17, animals with induction of chronic allergic pulmonary inflammation and use of Rho-kinase inhibitor and anti-IL17; SAL, saline group.
p < 0.05 compared with the SAL group.
p < 0.05 compared with the OVA group.
p < 0.05 compared with OVA-RHO inhibitor group.
p < 0.05 compared with OVA-anti-IL17 group.