Table 2.

Adjusted mean HCRU for endometriosis patients with opioid use in the United States.

Characteristics	High- vs low-risk opioid users				Chronic vs non-chronic opioid users
	High-risk opioid users	Low-risk opioid users	Estimated mean ratio with 95% CI	p-value	Chronic opioid users	Non-chronic opioid users	Estimated mean ratio with 95% CI	p-value
All-cause HCRU
Outpatient visits	17.49	15.51	1.13 (1.11–1.14)	<0.0001	19.53	15.00	1.30 (1.27–1.33)	<0.0001
ER visits	0.71	0.53	1.33 (1.29–1.39)	<0.0001	0.86	0.52	1.67 (1.58–1.77)	<0.0001
Inpatient visits	0.21	0.16	1.30 (1.23–1.38)	<0.0001	0.27	0.14	1.87 (1.72–2.04)	<0.0001
Total LOS	0.83	0.65	1.29 (1.17–1.42)	<0.0001	1.24	0.59	2.10 (1.80–2.46)	<0.0001
Pharmacy fills	19.58	16.88	1.16 (1.14–1.18)	<0.0001	23.18	16.43	1.41 (1.38–1.45)	<0.0001
Endometriosis–related HCRU
Outpatient visits	0.265	0.223	1.19 (1.11–1.28)	<0.0001	0.336	0.197	1.71 (1.53–1.91)	<0.0001
ER visits	0.008	0.004	1.87 (1.48–2.37)	<0.0001	0.012	0.004	3.19 (2.37–4.28)	<0.0001
Inpatient visits	0.008	0.006	1.42 (1.17–1.71)	0.0003	0.011	0.005	2.33 (1.80–3.01)	<0.0001
Total LOS	0.033	0.022	1.51 (1.10–2.07)	0.0101	0.043	0.019	2.27 (1.37–3.78)	0.0016
Pharmacy fills	0.054	0.056	0.98 (0.86–1.10)	0.6962	0.054	0.055	0.98 (0.79–1.22)	0.8585

CI: confidence interval; ER: emergency room; HCRU: health care resource utilization; LOS: length of stay.