Table 4.
Disease condition–related factors that showed significant association with antihypertensive medication adherence among hypertensive patients in Ethiopia, 2020.
| Study ID | Area | Outcome variable | Disease condition–related factors affecting adherence to antihypertensive medication (AOR and 95% CI) |
|---|---|---|---|
| Ali et al.19 | Northern Ethiopia | Adherence to antihypertensive medication | Being at the pre-hypertension class of BP (AOR = 0.052, 95% CI: 0.003–0.242) less adherent to medication Hypertensive heart disease (AOR = 21.737, 95% CI: 1.568–418.428) more non-adherent to medication |
| Ambaw et al.20 | Gondar | Adherence to antihypertensive medication | Controlled hypertension (AOR = 2.93, 95% CI: 1.73–4.96) more adherent to medication Without comorbidity (AOR = 2.50, 95% CI: 1.01–6.21) more adherent to medication Have only one comorbidity (AOR = 2.68, 95% CI: 1.07–6.71) more adherent to medication |
| Asgedom et al.21 | JUSH | Antihypertensive medication adherence | Comorbidity (AOR = 0.083, 95% CI: 0.033–0.207) more likely to be non-adherent |
| Dego and Bobasa25 | Jimma town | Antihypertensive medication adherence | No multivariable analysis (only p-value) |
| Demisew et al.26 | Debre Berhan | Adherence toward antihypertensive treatment | Comorbid heart disease (AOR = 0.043, 95% CI: 0.03–0.7) less adherent to medication Forget fullness of their drugs (AOR = 0.014, 95% CI: 0.02–0.116) less adherent to medication |
| Gebreyohannes et al.27 | UoG | Level of adherence to antihypertensive medications | Feel tiredness (AOR = 3.802, 95% CI: 1.723–8.391) more non-adherent to medication Muscle pain (AOR = 5.199, 95% CI: 1.407–19.214) more non-adherent to medication Poor sleep (AOR = 4.89, 95% CI: 1.578–15.160) more non-adherent to medication Symptoms caused them to change their antihypertensive drug taking behavior (AOR = 16.104, 95% CI: 4.164–62.290) more non-adherent to medication |
| Getenet et al.28 | Hawassa | Adherence toward antihypertensive treatment | No comorbidities (AOR = 3.14, 95% CI: 1.48–6.67) more adherent to medication Controlled BP (AOR = 2.35, 95% CI: 1.15–4.81) more adherent to medication |
| Hareri et al.29 | Adama | Adherence status | Comorbidities (AOR = 0.50, 95% CI: 0.290–0.893) less adherent to medication |
| Mekonnen et al.30 | Northwest | Adherence toward antihypertensive treatment | No comorbidity (AOR = 4.36, 95% CI: 1.34–14.11) more adherent to medication |
AOR: adjusted odds ratio; 95% CI: 95% confidence interval; JUSH: Jimma University Specialized Hospital; UoG: University of Gondar.