Table 2.

Basic diagnostic data extracted from the five articles included in the quantitative analysis.

Study ID	No. of case/control	miRNA	Level	Sample	Diagnostic power
					TP	FP	FN	TN	DOR	Sen	Spe
Rodrigo-Muñoz et al.55a	138/39	miR-320a	↑	Serum	130	19	8	20	21.95	0.941	0.514
Rodrigo-Muñoz et al.55b	138/39	miR-185-5p	↑	Serum	123	9	15	30	32.5	0.89	0.8
Rodrigo-Muñoz et al.55c	138/39	miR-144-5p	↓	Serum	81	9	57	30	24.73	0.587	0.774
Rodrigo-Muñoz et al.55d	138/39	miR-1246	↑	Serum	68	5	70	34	24.14	0.496	0.865
Karam and Abd Elrahman61a	100/100	miR-155	↑	Plasma	80	11	20	89	33.04	0.8	0.89
Karam and Abd Elrahman61b	100/100	Let-7a	↓	Plasma	85	10	15	90	85	0.85	0.9
Elbehidy et al.92	95/80	miR-21	↑	Serum	88	18	7	62	45.55	0.93	0.78
Wu et al.53	53/47	miR-1165-3p	↑	Serum	44	7	9	15	10.83	0.83	0.69
ElKashef et al.51a	30/30	miR-21	↑	Serum	30	2	0	29	NA	1	0.95
ElKashef et al.51b	30/30	miR-155	↑	Serum	30	0	0	30	NA	1	1

^{a, b, c, d}Independent study from the same article.

TP, true positive; FP, false positive; FN, false negative; TN, true negative; DOR, diagnostic odds ratio; Sen, sensitivity; Spe, specificity