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. Author manuscript; available in PMC: 2021 May 10.
Published in final edited form as: Biochemistry. 2020 Nov 2;59(44):4238–4249. doi: 10.1021/acs.biochem.0c00724

Figure 6.

Figure 6.

(Top) isothermal calorimetry (ITC) titration of FeHsARD with MMP-CTP. (Bottom) Integrated heat change (kcal/mol MMP-CTP) as a function of MMP-CTP to HsARD ratio (peptide/protein). Curve fitting yields an estimated Kd of ~10 μM.