Table 1.
Characteristics | Overall Cohort (n = 240) |
---|---|
Demographics | |
Male sex | 135 (56) |
Age, y | 51 [34-62] |
Race | |
White | 121 (50.4) |
Black | 100 (41.7) |
Othera | 19 (7.9) |
BMI | 28 [24-32] |
Medical history | |
Hypertension | 37 (15.4) |
Diabetes | 51 (21.3) |
Dyslipidemia | 79 (32.9) |
Coronary artery disease | 52 (21.7) |
Chronic heart failure | 51 (21.3) |
Stroke/transient ischemic attack | 13 (5.4) |
Atrial fibrillation | 63 (26.3) |
Myocardial infarction | 33 (13.8) |
Active smokers | 77 (32.2) |
Autoimmune diseases | 24 (10.0) |
TB | 2 (0.8) |
Chest radiation | 8 (3.3) |
Neoplastic diseases | 30 (12.5) |
Severe chronic kidney disease | 44 (18.4) |
Chest trauma | 4 (1.7) |
Recent cardiac procedure | |
Percutaneous coronary intervention | 7 (2.9) |
Pacemaker/cardiac ablation | 24 (10.0) |
Cardiac surgery | 19 (7.9) |
Therapies | |
Immunosuppression | 15 (6.3) |
High dose corticosteroids | 9 (3.8) |
Oral anticoagulation | 27 (11.3) |
Etiology | |
Idiopathic | 126 (52.5) |
Postcardiac injury | 79 (32.9) |
Other | 35 (14.5) |
Clinical presentation | |
Fever | 21 (8.9) |
Subacute presentation | 12 (5.1) |
Trauma | 5 (2.1) |
Pericardial effusion | 107 (47%) |
Severe pericardial effusion | 49 (20.6) |
Heart failure | 43 (18.1) |
Chest pain | 220 (93.2) |
Cardiac examination | |
Pericardial rub | 43 (18.5) |
Pulsus paradoxus | 10 (4.3) |
Kussmaul sign | 4 (1.7) |
ECG | |
PR depression | 70 (30.6) |
ST elevation | 104 (45.4) |
T wave inversion | 57 (24.9) |
Laboratory | |
WBC, No. ×103/mL | 9.4 [6.7-12.3] |
Neutrophils, No. ×103/mL | 6.7 [4.2-9.5] |
Lymphocyte, No. ×103/mL | 1.6 [1.0-2.0] |
Hemoglobin, g/dL | 12.1 [10.4-13.5] |
Platelets, No. ×103/mL | 240 [177-325] |
Creatinine, mg/dL | 0.89 [0.72-1.1] |
C-reactive protein, mg/dL | 10.0 [1.6-18.6] |
Erythrocyte sedimentation rate, mm/h | 52 [23-88] |
Troponin ≥ 0.20 ng/mL | 46 (27.5) |
Treatment at presentation | |
Nonsteroidal antiinflammatory drugs | 169 (70.7) |
Colchicine | 152 (63.6) |
Glucocorticoids | 29 (12.2) |
Surgical procedure | |
Pericardiectomy | 8 (3.3) |
Pericardial window | 7 (2.9) |
Pericardiocentesis | 27 (11.3) |
Outcomes | |
Composite outcomeb | 82 (34.2) |
Treatment failure | 17 (7.2) |
Recurrent pericarditis | 38 (15.8) |
Cardiac tamponade | 31 (13.0) |
Constrictive pericarditis | 9 (3.8) |
Death | 9 (3.8) |
Rehospitalization for any cause | 90 (37.7) |
The data are presented as No. (%) of all cases or as median [interquartile range].
Other includes Asian, Native American, Hispanic, or not specified.
Composite end point defined as the presence of any of the following: failure of treatment, recurrences, cardiac tamponade, constrictive pericarditis, or death.