Table 2.
Frequency and characteristics of acute care events (hospitalizations and emergency department visits) among 1741 Cure Glomerulonephropathy Network participants
| Acute Care Event | Age Group | Baseline Steroid Exposure | Overall (n=1741) | ||
|---|---|---|---|---|---|
| ≤18 yr (n=714) | >18 yr (n=1027) | Yes (n=586) | No (n=1155) | ||
| Infection-related eventsa | |||||
| Total | 134 | 93 | 129 | 98 | 227 |
| Hospitalizations, n (%) | 74 (55) | 59 (63) | 73 (57) | 60 (61) | 133 (59) |
| Emergency department visits, n (%) | 60 (45) | 34 (37) | 56 (43) | 38 (39) | 94 (41) |
| Patients with ≥1 infection-related event, n (%) | 93 (13) | 70 (7) | 98 (13) | 65 (7) | 163 (9) |
| Infection-related events per subject, n (%)a,b | |||||
| 1 | 71 (76) | 52 (74) | 76 (78) | 47 (72) | 123 (75) |
| 2 | 12 (13) | 14 (20) | 14 (14) | 12 (19) | 26 (16) |
| ≥3 | 10 (11) | 4 (6) | 8 (8) | 6 (9) | 14 (9) |
| Infection-related acute care events per 100 person-yr (95% CI)a | 13.2 (11.2 to 15.7) | 6.2 (2.1 to 7.6) | 11.2 (9.4 to 13.3) | 7.2 (5.9 to 8.8) | 9.0 (7.9 to 10.3) |
| Length of stay (d), median (IQR)c | 4 (2–6) | 4 (3–7) | 4 (2–7) | 4 (2–6) | 4 (2–7) |
| ICU stay due to infection, n (%)c | 8 (11) | 2 (3) | 6 (5) | 4 (4) | 10 (8) |
95% CI, 95% confidence interval; IQR, interquartile range; ICU, intensive care unit.
a
Inclusive of multiple infections within individuals.
b
Of number of subjects with ≥1 infection-related acute care event.
c
Of hospitalized infection-related acute care events only.