Table 3.
Descriptors of infection-related acute care events (hospitalizations and emergency department visits) by organ system and organism type among 1741 participants in the Cure Glomerulonephropathy Network study
| Infection Site and Type | Age Group, n (%) | Baseline Steroid Exposure, n (%) | Overall, n (%) (n=1741) | ||
|---|---|---|---|---|---|
| ≤18 yr (n=714) | >18 yr (n=1027) | Yes (n=586) | No (n=1155) | ||
| Primary site of infectiona | |||||
| Total infections | 134 (100) | 93 (100) | 129 (100) | 98 (100) | 227 (100) |
| Pulmonary/lower respiratory tract | 29 (22) | 27 (29) | 34 (26) | 22 (23) | 56 (25) |
| Upper respiratory tract/throat | 37 (28) | 11 (12) | 28 (22) | 20 (20) | 48 (21) |
| Gastrointestinal | 13 (10) | 13 (14) | 17 (13) | 9 (9) | 26 (11) |
| Multisystem infection | 19 (14) | 7 (8) | 13 (10) | 13 (13) | 26 (11) |
| Skin and soft tissue | 11 (8) | 12 (13) | 13 (10) | 10 (10) | 23 (10) |
| Genitourinary | 8 (6) | 11 (12) | 6 (5) | 13 (13) | 20 (9) |
| Bacteremia and septicemia | 8 (6) | 8 (9) | 10 (8) | 6 (6) | 16 (7) |
| Ear and nose | 6 (4) | 1 (1) | 4 (3) | 3 (3) | 7 (3) |
| Bone and joint | 1 (1) | 1 (1) | 2 (2) | 0 (0) | 2 (1) |
| Eye | 2 (1) | 0 (0) | 1 (1) | 1 (1) | 2 (1) |
| Central nervous system | 0 (0) | 2 (2) | 1 (1) | 1 (1) | 2 (1) |
| Organism typea | |||||
| Bacterial | 56 (42) | 50 (54) | 63 (49) | 43 (44) | 106 (47) |
| Viral | 53 (40) | 27 (29) | 45 (35) | 35 (36) | 80 (35) |
| Fungal | 1 (1) | 3 (3) | 2 (2) | 2 (2) | 4 (2) |
| Unknown | 24 (18) | 13 (14) | 19 (5) | 18 (18) | 37 (16) |
a
Infections occurring within 14 d of a previous infection of the same type or organ system were considered a single event.