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. 2020 Dec 9;7:572435. doi: 10.3389/fmed.2020.572435

Table 2.

Univariate and multivariate logistic regression analysis for total exacerbation.

Univariate model Multivariate model
OR (95% CI) P-value OR (95% CI) P-value
Sex
Female Reference Reference
Male 3.0394 (1.4362–6.4321) 0.004 3.6455 (1.1323–11.7361) 0.030
Age 1.0071 (0.9785–1.0365) 0.630 NA NA
Smoking index 1.0109 (1.0015–1.0203) 0.023 0.9999 (0.9872–1.0128) 0.993
BMI 0.9517 (0.8935–1.0138) 0.125 NA NA
SGRQ scores 1.0653 (1.0443–1.0866) <0.05 1.0395 (1.0140–1.0656) <0.05
GOLD stage
GOLD 1 Reference Reference
GOLD 2 2.0500 (0.8845–4.7511) 0.094 1.3233 (0.4750–3.6867) 0.592
GOLD 3 8.9167 (3.8123–20.8542) <0.05 2.6184 (0.8800–7.7903) 0.084
GOLD 4 9.3333 (3.0332–28.7195) <0.05 1.9026 (0.4135–8.7543) 0.409
COPD years 1.1208 (1.0536–1.1924) <0.05 1.1044 (1.0209–1.1947) 0.013
PLR 1.0093 (1.0044–1.0142) <0.05 1.0160 (1.0051–1.0270) 0.004
SII 1.0011 (1.0004–1.0018) 0.002 1.0002 (1.0000–1.0041) 0.086
SIRI 1.5203 (1.1914–1.9399) 0.001 1.3994 (0.9070–2.1592) 0.129
PLT/MPV 0.9909 (0.9502–1.0333) 0.669 NA NA
PLT/RDW 0.9966 (0.9335–1.0640) 0.919 NA NA

OR, odds ratio; CI, confidence interval; PLR, platelet–lymphocyte ratio; SII, platelet × neutrophil/lymphocyte; SIRI, monocyte × neutrophil/lymphocyte; PLT/RDW, platelet counts–red cell distribution width ratio; PLT/MPV, platelet counts–mean platelet volume ratio.