Table 2.
Personal and clinical characteristics of 183 COVID-19 patients with an abnormal liver function
| Liver tests | ||||
|---|---|---|---|---|
|
|
||||
| Characteristics | All patients (n = 183) | Mild liver injury (n = 103) | Moderate/severe liver injury (n = 80) | P value |
| Median (interquartile) age (years) (No (%)) | 56.00 (43.75–66.00) | 53.00 (41.00–62.50) | 57.00 (48.00–70.00) | 0.044∗ |
| Age groups (years) (No (%)): | No. (%) | No. (%) | No. (%) | |
| ≤18 | 5 (2.75) | 5 (4.85) | 0 (0.00) | |
| 19–40 | 28 (15.30) | 19 (18.45) | 9 (11.25) | |
| 41–65 | 99 (54.10) | 57 (55.34) | 42 (52.50) | |
| ≥66 | 51 (27.87) | 22 (21.36) | 29 (36.25) | |
| Sex (No (%)): | 0.644 | |||
| Male | 104 (56.83) | 57 (55.34) | 47 (58.75) | |
| Female | 79 (43.17) | 46 (44.66) | 33 (41.25) | |
| Coexisting conditions (No (%)): | ||||
| Any | 98 (53.55) | 44 (42.72) | 54 (67.50) | 0.001† |
| Hypertension | 51 (27.87) | 24 (23.30) | 27 (33.75) | |
| Diabetes | 44 (24.04) | 15 (14.56) | 29 (36.25) | |
| Chronic lung disease | 8 (4.37) | 2 (1.94) | 6 (7.50) | |
| Heart disease | 17 (9.29) | 6 (5.83) | 11 (13.75) | |
| Renal disease | 3 (1.64) | 0 (0.00) | 3 (3.75) | |
| Cancer | 2 (1.09) | 0 (0.00) | 2 (2.50) | |
| Pneumonia (No (%)) | 170 (92.90) | 92 (89.32) | 78 (97.50) | 0.033∗ |
| Bilateral involvement on chest radiographs (No (%)) | 157 (85.79) | 81 (78.64) | 76 (95.00) | 0.002† |
| Acute respiratory distress syndrome (No (%)) | 59 (32.24) | 24 (23.30) | 35 (43.75) | 0.003† |
| Secondary infection (No (%)) | 70 (38.25) | 33 (32.04) | 37 (46.25) | 0.050∗ |
| Antiviral | 108 (59.02) | 46 (44.66) | 62 (77.50) | 0.000† |
| Length of stay | 20.00 (15.00–28.00) | 17.00 (14.00–24.00) | 23.00 (20.00–33.50) | 0.001† |
Data are N (%) or median with 95% CI (IQR).
∗
P < 0.05,
†
P < 0.01 versus mild liver injury cases.