Table 1:
Characteristics of participants by level of microvascular brain disease at the 2nd brain MRI, ARIC 2004-2006.
| Overall N=907 | No lacune, WMH grade<2 n=335, 36.9% | Lacune or WMH grade≥2 n=521, 57.5% | Lacune and WMH grade≥2 n=51, 5.6% | |
|---|---|---|---|---|
| Age, mean (SD), years | 72.3 (4.4) | 70.4 (3.9) | 73.4 (4.3) | 73.8 (4.2) |
| Women, % | 62.0 | 60.6 | 63.2 | 58.8 |
| African-Americans, % | 49.4 | 47.5 | 51.3 | 43.1 |
| Education, % | ||||
| Less than high school diploma | 21.3 | 17.0 | 23.8 | 23.5 |
| High school diploma | 35.1 | 35.2 | 35.1 | 33.3 |
| More than high school diploma | 43.7 | 47.8 | 41.1 | 43.1 |
| BMI, mean (SD), kg/m2 | 28.5 (5.2) | 28.0 (5.0) | 28.9 (5.2) | 28.5 (5.8) |
| Smoking, % | ||||
| Never | 7.5 | 7.5 | 7.1 | 11.8 |
| Former | 36.3 | 33.4 | 36.9 | 49.0 |
| Current | 56.2 | 59.1 | 56.1 | 39.2 |
| Hypertension, % | 71.4 | 60.6 | 77.2 | 84.3 |
| Diabetes, % | 18.1 | 13.1 | 20.7 | 23.5 |
| CHD, % | 4.3 | 4.5 | 3.5 | 11.8 |
Grade of WMH categorized according to the Cardiovascular Health Study (CHS) rating scale.