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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Alzheimers Dement. 2020 Jun 26;16(9):1280–1292. doi: 10.1002/alz.12128

Fig 4. Conditional Manhattan plots of the conditional −log10 (FDR) values for SNP association with LOAD conditional with SNP association with PTSD.

Fig 4.

Fig 4.

Fig 4.

Conditional Manhattan plots show the FDR q value for SNP association with LOAD association conditional with SNP association for PTSD. Fig. 4A: Discovery sample. Fig. 4B. Replication sample. Genome-wide significant line (red) is drawn at −log10(1×10−5), suggestive line (blue) is drawn at −log10(0.05). Fig. 4C. Locus zoom plot of the region on chromosome 11 contains MS4A2 that was identified as associated with Q(LOAD|PTSD) for both the discovery and replication samples